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The effects of zoledronic acid are most likely due to
2019-05-16
The effects of zoledronic angiotensin ii are most likely due to impairment of the tumour-driven alterations to the bone microenvironment. This may render the bone marrow cavity unfavourable for metastatic growth, potentially redirecting tumour cells to other sites, including the periosteal surface.
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Introduction Dabigatran Boehringer Ingelheim Ingelheim
2019-05-16
Introduction Dabigatran (Boehringer Ingelheim, Ingelheim, Germany) is a direct thrombin inhibitor, which can be orally administered, and is used to decrease the risk of ischemic stroke in patients with non-valvular atrial fibrillation (NVAF). In early phase studies of dabigatran in healthy men, gal
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TCEP De hecho en una cultura como la
2019-05-16
De hecho, en una cultura como la mexicana de mediados del siglo xix, en que predomina la iconografía y símbolos tradicionales del catolicismo, la Crucifixión es de importancia fundamental, entendida a lo largo de El fistol del diablo a nivel de sinécdoque, es decir, de la parte por el todo: la herid
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La ignorancia que evidencia Xa Am
2019-05-16
La ignorancia que evidencia Xa. América poética respecto de los literatos mexicanos corrobora la falta de proximidad entre zonas tan distantes del orbe hispanoamericano. Al mismo tiempo comprueba el vacío biográfico que en este punto muestran las revistas mexicanas o, más exactamente, El Recreo de l
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Commission on Global Surgery s vision is universal access to
2019-05-15
Commission on Global Surgery\'s vision is “universal access to safe, affordable surgical and anaesthesia care when needed”. 5 billion people, largely the poor, marginalised, and rural, face impossible hurdles and for all practical purposes are excluded from what is often life-saving or disability-av
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The very fact that providing a greater
2019-05-15
The very fact that providing a greater number of doses of IPTp-SP is incrementally effective, even in settings where the parasite is sensitive, also highlights the potential benefit of interventions using more effective drugs. This finding means there is either scope to improve clearance of existing
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The medical environment in Asian Pacific countries
2019-05-15
The medical environment in Asian-Pacific countries is widely different from that in Western countries in terms of disease prevalence, CIED implant rates, and other parameters. Moreover, there are remarkable differences in the manner patients are followed-up among the countries in the Asian-Pacific r
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Table shows the results of achieving
2019-05-15
Table 3 shows the results of achieving ECV for atrial arrhythmia in this study. There was no significant between-group difference in the number of ECV attempts or the prevalence of successful ECV. The number of days to ECV in OAC-naïve patients was significantly less in the NOACs group (n=72) compar
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br Discussion Our results confirm that
2019-05-14
Discussion Our results confirm that germline variations in the TPMT gene are associated with treatment outcome in children with ALL [5]. The ability of TPMT to catalyze S-methylation and inactivate 6-mercaptopurine makes it a major determinant of 6-mercaptopurine toxicity. Furthermore, reduced TP
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br Discussion In the present report we describe a
2019-05-14
Discussion In the present report, we describe a technique for the sphingosine 1 phosphate receptor of a 6.0 Fr active fixation atrial lead in the inferior IAS using a 9.0 Fr GC. Previous studies have indicated that inferior IAS pacing significantly reduces paroxysmal AF burden and recurrence and
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El proyecto literario del conocido escritor mexicano Ignacio
2019-05-14
El proyecto literario del conocido escritor mexicano Ignacio Manuel Altamirano (1834–1893) ha sido ampliamente documentado en los estudios del siglo . Su propósito fue claro: instruir e inspirar al pueblo mexicano, cansado y desilusionado por la situación inestable del México decimonónico y por el s
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No en vano entre los a os http
2019-05-14
No en vano entre los años veinte y treinta el quehacer de Aub como viajante de comercio le lleva hcv protease inhibitors realizar numerosos viajes por Europa y a conocer de primera mano, ayudado de su condición políglota, las tendencias artísticas del momento, circunstancia a la que suma su particip
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br Possible reasons for the divergent
2019-05-13
Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site
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br The indications for ICD placement
2019-05-13
The indications for ICD placement for the secondary prevention of sudden cardiac death Some patients with underlying protoporphyrin ix disease and/or LV dysfunction die from tachyarrhythmias even after ICD placement [18]. However, no arrhythmic deaths occurred during the implantation or during th
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br We welcome the efforts by Robert Cohen
2019-05-13
We welcome the efforts by Robert Cohen and colleagues to promote country-specific targets for post-2015 health goals. Publications from the Consortium of Universities for Global Health () conference included a welcome focus on the building of effective global health education programmes. Histor
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