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br In some but not
2019-12-16
In some, but not all, human vessels, a small population of ETB (usually coronary N1-Methylpseudouridine sale with atherosclerotic lesions did not show any increase. In agreement, in experimental medicine studies in both heart failure patients and volunteer controls, selective ETA antagonism (BQ12
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br Materials and methods br
2019-12-16
Materials and methods Results Among 17,061 probes, the Benzoylmesaconitine of 758 probes (4.4%) showed at least a 2-fold upregulation (230 probes) or downregulation (528 probes) at day 3 after VMH lesioning as compared with sham-VMH lesioning. Supplement Table 1 shows the upregulated (>2-fold)
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br Multi subunit RINGs There are RING type E s
2019-12-16
Multi-subunit RINGs There are RING-type E3s that exist as multi-subunit assemblies (see Fig. 3B). A striking example is the Cullin RING Ligase (CRL) superfamily [35], which exhibits enormous plasticity in substrate specificity. Each CRL subfamily is characterized by a cullin protein (Cul-1, 2, 3,
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Initially the cause of hypoglycemia was not apparent
2019-12-16
Initially, the cause of hypoglycemia was not apparent. There was no detectable lesion in the pancreas on plain computed tomography, and anti-insulin antibody was negative. Eight hours after hospital admission, his son discovered that the patient had accidentally taken glimepiride 3mg/day for 3 days
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Total synthesis requires the two key intermediates and which
2019-12-16
Total synthesis requires the two key intermediates 3 and 7, which were synthesized using the route described in below. Phenylethylamine 3 was readily synthesized from vanillin or isovanillin; the overall yield was 50–52%. To prepare the intermediates 7, bromination of 2-(4-hydroxyphenyl) acetate wit
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zvad fmk br Discussion The aim of this study was
2019-12-16
Discussion The aim of this study was to establish staining protocols to enhance the visualization of a dental filling or its remaining in forensic dentistry. Teeth and dental materials resist to most of environmental and disaster conditions, therefore the forensic odontology exam is essential in
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In Hevea brasiliensis both the soluble
2019-12-16
In Hevea brasiliensis, both the soluble PPase and the membrane-bound V-PPase are present in the latex; the soluble PPase is in the C-serum (cytosol) of the latex [6] and the V-PPase is on the tonoplast of the lutoid, a special vacuole in the laticifers of rubber trees [7]. The V-PPase on the lutoid
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The crystal structure of the B subtilis Maf BSU was
2019-12-16
The crystal structure of the B. subtilis Maf (BSU28050) was published in 2000, and, to date, it represents the only experimental work with a purified Maf protein (Minasov et al., 2000). The structure revealed a structural fold similar to that found in ITPases and YjjX proteins, which are nucleotide
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Our results in the present study demonstrate that
2019-12-16
Our results in the present study demonstrate that CysLT1 mediates leukotriene-induced contraction in the fundus and suggest that both CysLT1 and CysLT2 mediate leukotriene-induced contraction in the antrum in vitro. Further studies on the effects of leukotrienes in vivo are required to elucidate the
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So far few studies have
2019-12-16
So far few studies have been conducted on the role of chemokines in patients with PTSD and avoidant personality disorders. Ogłodek et al. [10] in her studies found an increase in the level of the chemokine CCL-5 in patients with avoidant personality disorder and general anxiety disorder (GAD) as com
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Previous studies have shown the harmful
2019-12-16
Previous studies have shown the harmful effects of NEFA on ovarian functionality, such as inhibition of bovine granulosa cell survival and proliferation, steroidogenesis, and follicular development and alteration in oocyte development [36,45,46]. Therefore, the higher levels of NEFA found in the fol
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br Materials and methods br
2019-12-16
Materials and methods Results Discussion One novel finding in our study is that CK2 inhibition preserved axon function and structure in WM against ischemia. Consistent with these findings, oligodendrocytes, astrocytes, myelin, and Maraviroc were found to express CK2α. The robust expression
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br Materials and methods br Results br Discussion COX
2019-12-16
Materials and methods Results Discussion COX-2-mediated production of PGE2 is involved in cell growth and metastasis of many cancers. Previous studies indicated that COX-2 was overexpressed in many cancer tissues and that PGE2 increased cancer cell growth, a process that could be suppressed
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A growing body of data indicates that endothelial NOS
2019-12-16
A growing body of data indicates that endothelial NOS (eNOS) is a rate-limiting enzyme for the synthesis of nitric oxide (NO), its downstream sphingosine 1-phosphate receptor modulator molecule. High pathological concentrations of NO produced from inducible NO synthase (iNOS) induce apoptosis, wher
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br Conclusion br Conflict of interest br Author
2019-12-16
Conclusion Conflict of interest Author contributions Acknowledgements Piyamas Kanokwongnuwut was supported by the Development and Promotion of Science and Technology Talent Project (DPST), Royal Thai Government Scholarship. Funding for the work was provided by the Attorney General’s Depa
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