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These anatomical studies were followed by the
2022-11-08
These anatomical studies were followed by the first functional MRI studies of auditory processing in songbirds that were performed in starlings (Van Meir et al., 2005; De Groof et al., 2017; De Groof et al., 2013b) and in zebra finches (Boumans et al., 2008a; Boumans et al., 2007; Boumans et al., 20
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Different antioxidants were described as useful biomarkers i
2022-11-08
Different antioxidants were described as useful biomarkers in monitoring response to treatment in human and veterinary medicine [33,65,66]. In the same line, Thiol and TAC also proved to be useful biomarkers in monitoring the post-ovariohysterectomy period in queens with pyometra, since antioxidants
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Increasing evidence indicates that ILCs participate in a
2022-11-07
Increasing evidence indicates that ILCs participate in a dialog with CD4+ T HC-030031 [107–110]. This dialog is mediated, in part, through the expression of type II major histocompatibility complex (MHCII) molecules on ILC3s [107]. Depending on the expression of co-stimulatory molecules, MHCII:TCR i
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pmsf mg br AhR Modulators It is
2022-11-07
AhR Modulators It is now well recognized that ligand-activated AhR induces an immune tolerance response by acting directly on the antigen-presenting DCs and indirectly by increasing the population of immunosuppressive Tregs 24, 95, 96. In addition to inhibiting the formation or depleting the AhR
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Search sphere This sphere includes
2022-11-07
Search sphere 1: This sphere includes the ML-090 binding site between the α–γ subunits. The center point of the search area was located at x=35.26, y=77.67, z=137.74 and the initial search radius was set to 27Å which assures that the corresponding area outside the channel pore of the two subunits wa
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br Results br Discussion Although they do
2022-11-07
Results Discussion Although they do not have protein-coding capacity, lncRNAs make up a large part of the transcripts of the genome, and they play fundamental roles in carcinogenesis and osteosarcoma progression through regulation of tumor proliferation and metastasis. These lncRNAs include MA
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On the contrary evidence also suggests
2022-11-07
On the contrary, evidence also suggests that autophagy plays a striking protective role in cancer cells. Highly burgeoning cancer nonreceptor tyrosine kinase require cellular building blocks for their metabolism and energy production. At this stage of cancer development, autophagy acts as a friend p
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In our studies of leucine and BCH in pancreatic islets
2022-11-07
In our studies of leucine and BCH in pancreatic islets and clonal insulin cell lines, we noticed that leucine was a slightly stronger stimulant of insulin release. Previous studies showed that leucine can be metabolized to CO2[11], [12], [13], [14] and can increase acetoacetate in pancreatic islets
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br Material and methods br
2022-11-07
Material and methods Results Discussion T2D is a substantial threat to global human health [31]. Obesity-associated chronic low-grade inflammation promotes insulin resistance and T2D [32]. In obese individuals, the production of numerous inflammatory molecules including IL-6 and TNF-a is up
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To elucidate whether membrane fluidity changes could impact
2022-11-07
To elucidate whether membrane fluidity changes could impact on signaling pathways, we examined the effects of Rh2 on the activation of Akt, a lipid raft-associated protein kinase, which promotes cell survival and blocks the apoptotic pathways. Upon pretreatment with 5 mM MβCD and in the absence of R
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br Materials and methods br Results br Discussion Recently
2022-11-07
Materials and methods Results Discussion Recently, we showed that stimulation of TRPM3 and TRPC6 channels triggers a signaling cascade leading to the activation of AP-1 [11], [12], [13], [15]. The objective of this study was to investigate whether stimulation of TRPV1 channels leads to an a
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br Conclusions Extract of non
2022-11-05
Conclusions Extract of non-germinated winter rape seeds cv. Bellevue was screened for the aminopeptidase activity. It revealed broad substrate specificity, with the highest activity toward Phe-pNA. Also in the partially purified sample, phenylalanine was preferentially hydrolysed. PMSF, known ser
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Treatment of RAW cells with AP exosomes
2022-11-05
Treatment of RAW264.7 Biotin-16-dCTP receptor with AP(+)-exosomes caused an increase in their phagocytic activity. In the presence of amastatin, phagocytic activity was not completely suppressed, suggesting that at least two components were responsible for the activity; one of which is aminopeptidas
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Introduction Inflammasomes are large cytosolic protein compl
2022-11-05
Introduction Inflammasomes are large cytosolic protein complexes with multiple components that trigger a rapid immune response against pathogen-associated molecular pattern 822 (PAMPs) during pathogen infections or damage-associated molecular pattern molecules (DAMPs) during tissue damage [1]. Acti
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tamoxifen citrate br Conflict of interest statement br Intro
2022-11-05
Conflict of interest statement Introduction Human saliva contains many detoxifying and antioxidant tamoxifen citrate like glutathione S-transferase, catalase, peroxidase, aldehyde dehydrogenase (ALDH), etc. [1]. Human salivary ALDH (hsALDH) protects individuals from toxic aldehydes contained
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