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LDS BBs were found to
2018-10-29
LDS BBs were found to respond to ET-1 stimulation with a decrease in cell shortening. Furthermore, our findings that BQ123, but not BQ3020, blocked the negative shortening response to ET-1 are consistent with those of Izumi and co-workers (Izumi et al., 2000) and indicate an ETA receptor-mediated ef
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Recently the properties of self renewa http www apexbt
2018-10-29
Recently, the properties of self-renewal and pluripotency of human embryonic stem Myriocin (hESCs) have paved the path for such studies (Koch et al., 2009; Yiping Yan et al., 2005). The in vitro differentiation of hESCs to neuronal cells serves as a model for study of early human neuronal developme
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To identify a molecular marker that can serve as an
2018-10-29
To identify a molecular marker that can serve as an indicator of the differentiaion potential of the cell lines tested, we analyzed the Cy3 hydrazide levels of a group of genes in hESCs that include pluripotent transcription factors, modulators of various signaling pathways known to be involved in
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HOBt Supplier One limitation of using iPSCs is
2018-10-29
One limitation of using iPSCs is the inability to carry out studies under genetically defined conditions, leading to increased experimental variability. To overcome these obstacles, we used a zinc-finger-nuclease (ZFN)-mediated gene-editing technique (An et al., 2012; Corti et al., 2012; Li et al.,
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Last but not least the differentiation method described here
2018-10-29
Last, but not least, the differentiation method described here can be refined to be fully defined and xeno-free by substituting human serum albumin (HSA) present in RegES− medium with recombinant HSA (He et al., 2011) and using a higher certificate, xeno-free version of CnT-30 medium (CELLnTEC Advan
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glycogen phosphorylase In our study ERK and JNK inhibitors e
2018-10-26
In our study, ERK and JNK inhibitors effectively inhibited the migration of glioma glycogen phosphorylase while the effect of the p38 inhibitor was not as significant. Hence, we further evaluated the effect of downregulation of uPAR and cathepsin B on the expression of ERK and JNK. Reduction in the
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br Conclusions The data presented here
2018-10-26
Conclusions The data presented here demonstrate that MSX2 induces dedifferentiation with partial cell cycle re-entry in postmitotic multinucleated mammalian muscle cells. Our pharmacological treatment recapitulates MSX2-induced dedifferentiation and exhibits potential for future therapeutic proto
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br Results br Discussion In
2018-10-26
Results Discussion In this study, we identified the existence of non-neuronal ACS in developing prostate epithelium. Activation of ACS promoted the proliferation of epithelial progenitor check details and inhibited their differentiation to luminal cells. On the contrary, blockade of CHRM3 eff
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The Mx Cre system can be potentially associated
2018-10-26
The Mx1-Cre system can be potentially associated with additional problems. For instance, pIpC administration has been suggested to trigger HSC cycling, similar to interferon itself (Essers et al., 2009; Gidali et al., 1981; Sugiyama et al., 2006). While we found less evidence for a dramatic effect o
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The solution of the original problem taking into
2018-10-26
The solution of the original problem (17), taking into account the formula for beam function (14) and infinite series (33), can be written as where , and (y) is determined by formula (34). Since replacing the complex parameter (k=1, 2,…) by a conjugate value (it is also a root of Eq. (21)) causes
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In this study we extend the prior preliminary
2018-10-26
In this study, we extend the prior preliminary findings of the CCHN longitudinal study examining the patterns of AL by poverty group and race and ethnicity over the first year postpartum to determine whether levels of inequality are stable or dynamic during this period (Shalowitz et al., unpublished
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Use of different types of government metrics
2018-10-26
Use of different types of government metrics may yield important findings. Bischoff (2008) reported that the proliferation of school districts increase multiracial segregation between districts. In the historical data of government census, school districts showed a different pattern of growth from o
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The broad societal changes that
2018-10-26
The broad societal changes that are driving African women to marry at older ages, and thus experience prolonged risk of having a premarital birth, could, however, condition the experience of having a premarital birth in a way that lessens its consequences for children (Garenne & Zwang, 2006a). One s
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There is evidence indicating literacy has a protective
2018-10-26
There is evidence indicating literacy has a protective effect on depressive symptoms (Barnes, Tager, Satariano, & Yaffe, 2004; Gordon, Hampson, Capell, & Madhok, 2002; Sudore et al., 2006). A randomized controlled trial of adults with depression and limited literacy demonstrated combining depression
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The notion that pets can facilitate
2018-10-26
The notion that pets can facilitate social capital goes beyond the more commonly investigated role of pets as a social icebreaker between strangers, or as a catalyst for social interaction (Hunt, Hart, & Gomulkiewicz, 1992; McNicholas & Collis, 2000; Messent, 1983; Newby, 1997; Robins, Sanders, & Ca
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