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br Convergence study and computational results To
2018-11-14

Convergence study and computational results To adequately choose the size of the finite elements and the integration step, we examined the convergence of the results as a function of these parameters. Given the physical nature of the simulated vibration process, the grid dimension and the integra
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To support claims of benefit in terms of reduced
2018-11-14

To support claims of benefit, in terms of reduced environmental burden or increased process sustainability, rigorous process analysis is required using tools such as Life Cycle Assessment or carbon- and water footprinting. These approaches require availability of material and nmda receptor antagonis
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br Nanobody mediated Drug Delivery Several researchers explo
2018-11-14

Nanobody-mediated Drug Delivery Several researchers exploited currently available nanobodies against tumor-specific receptors as conduits for delivering toxins or drugs to tumors, thereby reducing nonspecific toxicity to normal TGF-beta Smad Compound Library and diminishing side effects. The lac
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br Genetic Variability of HEV and Clinical Implication Seven
2018-11-14

Genetic Variability of HEV and Clinical Implication Seven HEV genotypes are recognized within the Orthohepevirus A species based on the HZ-1157 of entire viral genomes (HEV-1 to HEV-7) (Smith et al., 2016). Four HEV genotypes (HEV-1 to HEV-4) are well recognized as human pathogens while HEV-5 an
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In this issue of Castanho
2018-11-14

In this issue of Castanho and colleagues () address whether cognitive tests performed using videoconferencing could provide comparable diagnostic information as an in-clinic evaluation. They studied 69 individuals, aged 57 to 95years, across the diagnostic spectrum from normal to dementia and in va
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Pharmacophore hybridization a classical medicinal chemistry
2018-11-14

Pharmacophore hybridization, a classical medicinal chemistry strategy, is used widely in drug discovery (Fisher et al., 2014; Romagnoli et al., 2014; Solomon et al., 2010). As described herein, we introduced the pharmacophores of marketed anti-cancer agents into the scaffold of ARS to prepare deriva
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MITF has previously been described
2018-11-14

MITF has previously been described as having both oncogenic and tumour suppressor properties within melanoma (Hartman and Czyz, 2015; Levy et al., 2006). This idea is further perpetuated by the fact that while BRN2 and MITF have been shown to be expressed in two mutually exclusive populations, BRN2
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This study has several limitations First only papers
2018-11-14

This study has several limitations. First, only papers published in English were included. Publications in languages other than English were excluded due to insufficient information, which may lead to selection bias. Second, this study involved largely Asians and Caucasians; other ethnic subgroups (
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br Acknowledgments The authors wish to acknowledge co
2018-11-14

Acknowledgments The authors wish to acknowledge co-funding of this work by Spain׳s Ministry of Economy and Competitiveness (MINECO-INIA-CCAA) and the European Fund of Regional Development (FEDER, Grant RTA2011-00020-C02-02). The staff at the Central Service for Research Support (SCAI) of the Univ
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This work was completed following a previously described
2018-11-14

This work was completed following a previously described case-control study design [1]. Briefly, the evaluation of pro-inflammatory C-C chemokine profiles association with injectable insulin use and BC outcomes was carried out under two protocols approved by both Roswell Park Cancer Institute (EDR15
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br Acknowledgements This study was
2018-11-14

Acknowledgements This study was supported by a Grant from the Smoking Research Foundation (URL: http://www.srf.or.jp/english/index.html), Grant-in-Aid for Scientific Research on Innovative Areas 26118701, 26120701(Y.O.), and Grant-in-Aid for Young Scientists (A) 25713043 (Y.O.) from the Ministry
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In this analysis the PCI values
2018-11-14

In this analysis, the PCI values of less than 10 represent a uniform distribution of rainfall (i.e. low Apremilast Supplier concentration); the PCI values between 11 and 15 denote a moderate precipitation concentration; values from 16 to 20 denote irregular distribution and values above 20 represent
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Replicating prior studies we found that non anxious individu
2018-11-14

Replicating prior studies, we found that non-anxious individuals are capable of learning from positive outcomes, regardless of age (Moutsiana et al., 2013). However, this ability was impaired in both anxious adolescents and adults. Although anxious adolescents recalled expected coelenterazine from
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We anticipated that punishment of excluders would be associa
2018-11-14

We anticipated that punishment of excluders would be associated with increased activity in the pre-SMA/ACC and AI (Sanfey et al., 2003; Strobel et al., 2011). In contrast, forgiveness was expected to be associated with increased activity in the dmPFC, TPJ and lPFC (Brüne et al., 2013; Will et al., 2
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br What are the basic attention mechanisms
2018-11-13

What are the basic attention mechanisms behind attentional bias? Attention is not a single construct, but rather constitutes a series of mechanisms and processes that are both distinct and interrelated (Raz and Buhle, 2006). That is, while sub-components of attention are thought to play specializ
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