• In this study we analyzed

  2019-04-25

  

  In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation p-gp inhibitors list and/or the

• br Discussion CML was the first malignancy

  2019-04-25

  

  Discussion CML was the first malignancy to be linked to a clear genetic abnormality, the Philadelphia chromosome. This chromosomal abnormality is so named because of the city in which it was first discovered and described in 1960 by Peter Nowell and David Hungerford [1]. The fusion protein result

• Introduction Myelodysplastic Syndrome MDS is a heterogeneous

  2019-04-25

  

  Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal

• br The UN high level

  2019-04-25

  

  The 2016 UN high-level Summit for Refugees and Migrants in New York (NY, USA) provided a historic opportunity to engage world leaders in responding to the health dimensions of mass migration. Despite the magnitude of the phenomenon and its potential for changing global as well as national health p

• br Materials and methods br Conflict of interest statement

  2019-04-25

  

  Materials and methods Conflict of interest statement Acknowledgements This work was supported by the National Natural Science Foundation of China (No: 31100781); the Natural Science Foundation of Hebei Province, PR China (No: C2011206040); and the Department of Health of Hebei Province (No:

• glutathione s-transferase br Possible reasons for the diverg

  2019-04-25

  

  Possible reasons for the divergent results for the predictive value of PES for cardiac events First, there were methodological differences in the stimulation protocols used for PES, including the number of extrastimuli, the minimum coupling interval used (up to 200ms or refractoriness), the site

• purchase LDE225 Lead fracture was observed in of leads

  2019-04-25

  

  Lead fracture was observed in 4 of 1092 leads (0.37%); verified and incomplete lead fractures were observed in three (0.27%) and one lead (0.09%), respectively. All these fractures occurred in leads implanted by the SVP method; no fractures were observed in leads implanted by the CVC method (p Disc

• Bile acids are cholesterol derivatives

  2019-04-25

  

  Bile acids are cholesterol derivatives produced only in the hepatocytes of the liver. Hepatic bile acid synthesis represents the only quantitatively significant route for cholesterol elimination. Bile acids are amphipathic physiological detergents that facilitate dietary cholesterol, lipid and fat-s

• March marked annual World TB

  2019-04-25

  

  March 24 marked annual World TB Day, this year\'s theme being “reach the 3 million” who acquire tuberculosis every year but who do not get diagnosed, treated, or cured. Why do so many patients with this life-threatening infectious disease go under the radar? One reason, as Madhukar Pai and colleague

• br Interpretation of identified genetic variants

  2019-04-24

  

  Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected

• Rollout of Avahan programme activities began in

  2019-04-24

  

  Rollout of Avahan programme activities began in January, 2004, reaching almost all districts by mid-2005, and with rapid scale-up within each district. By December, 2008, more than 75% of the estimated target populations of female sex workers (total population 217 000) and high-risk men who have sex

• El reclutamiento era una tarea permanente

  2019-04-24

  

  El reclutamiento era una tarea permanente de los grupos guerrilleros, en el caso de las mujeres, generalmente mantenían relaciones estrechas con miembros activos de la guerrilla. Hermanos, parientes o amigos sostenían discusiones en el seno familiar sobre las condiciones de injusticia social, repres

• br Eva Leticia Ordu a Trujillo investigadora del en uno

  2019-04-24

  

  Eva Leticia Orduña Trujillo, investigadora del en uno de sus más recientes libros , aborda un tema fundamental para explorar, debatir y profundizar sobre nuestras aún muy débiles democracias latinoamericanas, LY2228820 través de la actuación de nuestros estados en sedes judiciales internacionales.

• En muchos estudios fuera del campo posfundacional la referen

  2019-04-24

  

  En muchos estudios (fuera del campo posfundacional) la referencia gpr119 agonist Laclau proviene de teorizar el “discurso populista”. Existe un frecuente equívoco que es interpretar esto como una reducción a una especie de lenguaje populista. Al respecto, el esfuerzo de Laclau por establecer el esta

• The type of ventricular arrhythmia monomorphic VT or polymor

  2019-04-23

  

  The type of ventricular arrhythmia (monomorphic VT or polymorphic VT/VF) responsible for the electrical storm provides an important diagnostic clue to its pathophysiology (Fig. 1). In this review, we address the diagnosis and specific treatments according to the type of ventricular arrhythmia and th

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