• The concept of substrate mapping and ablation evolved

  2019-06-11

  

  The concept of substrate mapping and ablation evolved from these surgical experiences. Unlike surgeons who can visually identify the infarct region, electrophysiologists must locate the abnormal region using the guidance of local ventricular electrograms. Marchlinski et al. reported that voltage map

• Patients with heart failure are at a

  2019-06-11

  

  Patients with heart failure are at a high risk of mortality and morbidity. Medical expenses associated with heart failure are increasing, and approaches aimed at early heart failure detection and reduction of the hospitalization rate are yet to be developed. Patients with CIEDs also develop heart fa

• br Conflict of interest br Introduction

  2019-06-11

  

  Conflict of interest Introduction Nasopharyngeal carcinoma (NPC) is a tumor arising from the epithelial cells that line the surface of the nasopharynx. It is a commonly found tumor of the head and neck region in adults, and its incidence varies widely in different regions. It has been observed

• flavopiridol We herein report a patient with dMMR and MSI H

  2019-06-11

  

  We herein report a patient with dMMR and MSI-H metastatic gastric cancer who flavopiridol responded favorably and durably to PD-1 blockade. This patient, along with the previous two demonstrated by Le et al, are up-to-date the only 3 MMR gastric cancer patients who responded well to PD-1 blockade.

• Los v nculos que el ensayista conserv con los intelectuales

  2019-06-10

  

  Los vínculos que el ensayista conservó con los intelectuales mexicanos fueron profusos y perdurables, en tanto continuaron hasta sus últimos años de vida, aun durante su estadía en la Cuba revolucionaria de principios de los años sesenta. Así, en 1959 inició lo que Ángel Rama denominó el ciclo cuban

• Fourth social rehabilitation and reintegration

  2019-06-10

  

  Fourth, social rehabilitation and reintegration of patients with fistula along with estrone sensitisation (to prevent the occurrence of fistula, as well as to mitigate against stigmatisation of fistula survivors) will be crucial to eliminate obstetric fistula. Many women might not seek surgical care

• For most health care professionals infectious disease modell

  2019-06-10

  

  For most health-care professionals, infectious-disease modelling is something of a black box. One can see the input assumptions (ie, what goes in) and the outputs (ie, what comes out), but what happens in between seems close to magic. Given their complexity, to understand any one of the models used

• br Intrauterine insemination IUI is one of the more

  2019-06-10

  

  Intrauterine insemination (IUI) is one of the more widely used fertility treatments, and often suggested as the first choice for infertile couples with cervical infertility, mild male factor infertility, anovulation, mild or minimal endometriosis, and unexplained infertility with at least one pate

• Our group then carried out a study to determine

  2019-06-10

  

  Our group then carried out a study to determine the substrate sites and arrhythmogenic mechanisms of the BrS [29]. We found that all our BrS patients had abnormal low voltage, fractionated late potentials exclusively clustering in the anterior aspect of the RVOT epicardium and not seen anywhere else

• To date over mutations in KCNQ have

  2019-06-10

  

  To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [

• HIV counselling and testing is the essential first step

  2019-06-10

  

  HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase

• Tobacco use is poised to kill

  2019-06-10

  

  Tobacco use is poised to kill as many as 1 billion people in the 21st century, primarily from non-communicable diseases. Less often noted is the effect of tobacco use and second-hand smoke exposure on maternal and child health. Cigarette smoking during pregnancy poses serious risk to the mother and

• One year after her initial

  2019-06-10

  

  One year after her initial diagnosis, the patient presented back for the abrupt onset of symmetrical bilateral lower-limb weakness and numbness. The patient did not report other symptoms or history of trauma. Clinical examination revealed a healthy person except for a symmetrical proximal and distal

• Tedizolid HCl cost br The world population faces

  2019-06-10

  

  The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures

• Cardiac fibroblasts express various ion

  2019-06-10

  

  Cardiac fibroblasts express various ion channels, in particular voltage-gated K BB-94 and nonselective cation channels of the transient receptor potential (TRP) family . Both K and TRP channels are important determinants of fibroblast function, with TRP channels acting as Ca entry pathways that sti

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