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Un giro lo hemos dicho es una transformaci
2018-10-25
Un giro —lo hemos dicho— es una transformación, un desplazamiento en la manera de hacer las cosas; en un momento, supone un balbuceo sin parar, un desborde de ideas y posibilidades, nos dice Irit Rogoff (2011); y digo que es este balbuceo y este desborde el que me toma, cuando vivo la vejez de mi ma
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Bol var Echeverr a denomin
2018-10-25
Bolívar Echeverría denominó la de la modernidad a01 la expansión, y —a largo plazo— a la imposición, de la perspectiva estadounidense en el desarrollo de la ciencia y la cultura. Durante el siglo , el modelo norteamericano se instaló más allá de sus fronteras originales, introduciendo una “artifici
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br S Monsi ten as
2018-10-25
Sí Monsi, tenías dos maneras de acercarte cuando sonaba el timbre del teléfono en casa y Plerixafor tú. El uno era un tono de urgencia que implicaba la necesidad apremiante de comentar algún acontecimiento político, para lo que cualquier tipo de cortesía te parecía una pérdida de tiempo y, sin s
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Como hab amos afirmado previamente los espacios en la obra
2018-10-25
Como habíamos afirmado previamente, los espacios en la obra de Eltit son múltiples, cambiantes, movibles y alegóricos, y comprenden principalmente lugares abiertos que no se configuran de forma homogénea, sino por medio de matices. Para Brito (2014), el espacio en la obra de Eltit es un escenario do
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br Conclusion br Introduction Atrophic maxilla or
2018-10-25
Conclusion Introduction Atrophic maxilla or mandible can lead to lack of prosthesis retention because of an inadequate bearing area causing both functional and physiological problems for patient, these problems can be treated for patient satisfaction with an implant supported fixed or removabl
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Third institutional investors may own stocks of firms not on
2018-10-25
Third, institutional investors may own stocks of firms not only because of their social and environmental reputation, but also for their financial performance (Johnson & Greening, 1999). This is because “socially responsible investors are clearly not interested in considering unprofitable investment
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Thirdly we can report that La induced effects are
2018-10-24
Thirdly we can report that La-induced effects are ROS-dependent and can therefore be reversed by the addition of antioxidants such as AA, NAc, and LA. Although no data is available on the effects of La on C2C12 differentiation, numerous studies exist elucidating the question how ROS influence this p
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br Materials and methods br Author disclosure
2018-10-24
Materials and methods Author disclosure statement 5. Acknowledgments This work was supported by the UK Medical Research Council grants G0701172 and G0801061. We thank Dr. Yacoub Khalaf, director of the Assisted Conception Unit of Guy\'s and St. Thomas\' NHS Foundation Trust and his staff f
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Recently work has been focused on
2018-10-24
Recently, work has been focused on the adipose tissue-derived stromal cell (ASCs) population, since retrieval is straight forward and non-harmful coupled to low-risk surgical procedures. However, biological properties of ASCs have only been assessed by indiscriminate isolation from mostly white fat
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We have demonstrated that donor specific
2018-10-24
We have demonstrated that donor-specific DNAm patterns are maintained upon reprogramming into iPSCs (Shao et al., 2013), and these also remain upon redifferentiation into iPS-MSCs. Thus, there is some epigenetic memory after chromatin remodeling—whether these donor-specific DNAm patterns are functio
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bosentan A recent study indicated that XIST expression can b
2018-10-24
A recent study indicated that XIST expression can be lost upon prolonged passaging of female hiPSCs, referred to as “erosion of XCI” (Mekhoubad et al., 2012). This epigenetic erosion was found to be irreversible and correlated with a loss of differentiation characteristics and is very relevant for d
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Our selection free targeting approach enables rapid generati
2018-10-24
Our selection-free targeting approach enables rapid generation of knockin reporter lines, though it also requires either using established iCas9 SR 3576 or creating new iCas9 lines in a desired hPSC background. The upfront effort for generating iCas9 cells is relatively small due to the efficient T
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To establish whether replacement of lost podocytes by
2018-10-24
To establish whether replacement of lost podocytes by RPCs could influence CKD outcome, we traced podocyte regeneration to compare mice that underwent proteinuria remission with those that developed persistent proteinuria and CKD using two different lineage-tracing strategies. By tracking podocytes
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ESC CMs can be subdivided into atrial and
2018-10-24
ESC-CMs can be subdivided into atrial and ventricular CMs (Burridge et al., 2012). It has been documented that the expression of the α-isoform of myosin heavy chain (α-MHC), MLC2a, and MLC1a become restricted to the atrium during murine development (Zammit et al., 2000). Here, we employed MLC2a and
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Gpr or T cell death associated gene Tdag is
2018-10-24
Gpr65, or T cell death-associated gene 8 (Tdag8), is a proton/acid-activated GPCR (Choi et al., 1996; Wang et al., 2004). Whereas GPR65 had not been linked to HSPC transitions, it was reported to be a pro-apoptotic factor in glucocorticoid-induced lymphocyte apoptosis (Malone et al., 2004) and to re
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