• Introduction The Space Shuttle has been retired and the Inte

  2019-06-28

  

  Introduction The Space Shuttle has been retired and the International Space Station (ISS) will be in use until 2020 (Fig. 1). Scientists and engineers are thinking about a mission to Mars in the future. Human exploration of space is at a turning point, and a number of questions about the future of

• Performing an ajmaline test in

  2019-06-28

  

  Performing an ajmaline test in children is problematic for 2 reasons. First, the test is apparently less sensitive in children than in adults. In fact, in 1 study, a repeat ajmaline challenge performed after puberty unmasked BrS in 23% of relatives with a previously negative drug test performed duri

• The launches in London and Boston were just

  2019-06-28

  

  The launches in London and Boston were just that; the beginning of an education and advocacy campaign intended to highlight the pivotal role of surgical care in health system strengthening. The formal Commission report, 32 000 words of synthesis, analysis, recommendations, and indicators, is only on

• therefore Since antithrombotic therapy for patients with

  2019-06-27

  

  Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame

• br Discussion and outstanding questions Reproductive endocri

  2019-06-27

  

  Discussion and outstanding questions Reproductive endocrine hormones such as inhibin affect breast cancer cell survival in the primary tumour and affect tumour homing and survival in the bone microenvironment. The molecular mechanism driving this effect of hormones in bone is likely to be multifa

• Interpretation The SMART course can give orthopaedic

  2019-06-27

  

  Interpretation The SMART course can give orthopaedic surgeons practising in LMICs the skills and knowledge to successfully perform flaps and reduce amputation. While this MOG (35-55) course offers a collaborative, sustainable approach to reduce global surgery disparities in amputation, future inves

• br Case report A year old man with

  2019-06-27

  

  Case report A 63-year-old man with a history of longstanding atrial fibrillation (AF) was admitted to our hospital with anterior acute myocardial infarction (AMI). Emergency cardiac catheterization revealed chronic total occlusion of the distal right coronary artery, total occlusion of the proxim

• Besides the possibility of a tumor with spontaneous regressi

  2019-06-27

  

  Besides, the possibility of a tumor with spontaneous regression seem not to be associated with tumor size, tumor number, the level of serum alpha-fetal protein presence or not of distance metastasis distance metastasis. Two common mechanisms of HCC with spontaneous regression were suggested: tumor h

• Recently denosumab demonstrated a significant delay in

  2019-06-27

  

  Recently, denosumab demonstrated a significant delay in the onset of detectable bone lesions in men with castration resistant prostate cancer compared to placebo . This could indicate some kind of efficacy of the compound as anticancer agent and consequently an indirect confirmation of the role of R

• Cisatracurium Besylate molecular br Case report His physical

  2019-06-27

  

  Case report His physical examination and basic laboratory data were normal. No organic heart disease other than dextrocardia was detected on electrocardiography, chest radiography, and echocardiography (Fig. 1). A head-up tilt test (HUT) was performed according to the ESC/ACC guidelines [7,8]. T

• La pregunta que fundamenta esta investigaci n es acerca de

  2019-06-27

  

  La pregunta que fundamenta esta investigación es acerca de la posibilidad de que los participantes de experiencias de acción colectiva urbana definan y re-definan sus pertenencias Histamine Phosphate la región y las naciones en las que se insertan. Este acercamiento a las representaciones que los su

• In primary diagnosis IKZF status

  2019-06-27

  

  In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19

• Rabies has no cure and by the

  2019-06-26

  

  Rabies has no cure, and by the time of clinical onset it is invariably fatal. More than 95% of deaths occur in Africa and Asia, 80% of which are in people living in rural, underserved populations, most of whom are children. Community awareness about the power of preventing dog bites and of life-savi

• All statistical analyses were performed using

  2019-06-26

  

  All statistical analyses were performed using SPSS software (version 15; SPSS Inc., Chicago, IL, USA). Continuous data are expressed as mean (standard deviation) and were analyzed with two independent-samples tests. Chi-square and Fisher\'s exact tests were used for categorical data. The significanc

• br Conflict of interest br Introduction br Baseline ablation

  2019-06-26

  

  Conflict of interest Introduction Baseline ablation strategies targeting PVs It is well known that PVI was first developed to eliminate the triggers that initiate attacks of paroxysmal atrial fibrillation [1]. Subsequently, the additional function of the PV myocardium to perpetuate atrial f

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